Definition of Modafinil | Buying Modafinil Online | Mechanism of Action | Side Effects | Contraindications | FAQs
Modafinil: is this drug secure for patients or is it ineffective at all? Let’s sort out who may require Modafinil and discover other useful information on this medication.
Modafinil: Comprehensive and Helpful Review of This Medicine
In an era where productivity and concentration are highly valued, people are searching for methods to optimize their mental performance all the time.
One noteworthy variant that has grabbed the consideration of individuals is Modafinil.
This prescription drug has become popular as a cognitive enhancer. It is regarded as a helpful medication for its ability to contribute to wakefulness and improve focus.
This overview covers detailed information about Modafinil starting from the benefits of this drug to its potential risks.
Definition of Modafinil
Modafinil is a prescription drug that is commonly employed to raise wakefulness and improve vigilance in people who experience excessive sleepiness because of definite sleep disorders.
The Modafinil medication is approved by the U.S. Food and Drug Administration (FDA) under the brand name Provigil.
Modafinil was originally created to treat such conditions as narcolepsy, sleep apnea, shift work sleep disorder, etc. However, nowadays, this drug has obtained popularity beyond its approved medical uses.
According to some data, Modafinil has cognitive-enhancing effects and is usually employed not for its intended purpose as a “smart drug”. Lots of people, in particular, learners, experts, and those individuals who aim to enhance concentration and productivity, decide to purchase the Modafinil drug to improve their cognitive abilities.
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- Medication: Modafinil (brand name: Provigil, Modalert, Nuvigil, )
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Modafinil Indications
Modafinil is a non-amphetamine central nervous system stimulant that has properties promoting wakefulness. This drug is employed to treat conditions that create excessive daytime sleepiness.
According to https://www.ncbi.nlm.nih.gov/books/NBK531476/, there are FDA-approved indications and off-labeled indications of Modafinil.
Narcolepsy, shift work sleep disorder, and obstructive sleep apnea are referred to as FDA-approved indications.
Meanwhile, attention-deficit hyperactivity disorder, acute unipolar and bipolar depressive episodes, cocaine dependence, cancer-related fatigue, and multiple sclerosis-related fatigue are referred to as off-labeled indications of the Modafinil medicine.
Mechanism of Action of Modafinil
The Modafinil drug is classified as a eugeroic, which implies it contributes to wakefulness.
Since Modafinil was created for the treatment of sleep disorders, in particular, narcolepsy initially, it operates by affecting definite brain chemicals that take part in sleep and wakefulness regulation.
The Modafinil medication doesn’t cause feelings of nervousness or excessive stimulation in comparison to traditional stimulants.
Instead, Modafinil improves cognitive function by affecting neurotransmitters such as dopamine, norepinephrine, and others.
By raising the levels of these chemicals, the Modafinil drug assists individuals in feeling more alert, concentrated, and better prepared to solve mental tasks.
Modafinil Administration
Modafinil medicine is accessible exclusively in the form of 100 mg and 200 mg oral tablets. The usual dose of this medication is 200mg one time per day. Modafinil is classified as a control substance class IV drug.
The advisable dose of Modafinil tablets for treating narcolepsy or obstructive sleep apnea is 200 mg orally administered one time per day in the morning.
If you intend to treat shift work sleep disorder with Modafinil, you should take 200 mg one time per day approximately one hour before the start of the work shift.
Potential Side Effects
Modafinil is commonly regarded as a well-tolerated stimulant. The most widely reported side effects of this medication are headache, nausea, and decreased appetite.
Other widespread reported side effects of Modafinil may involve anxiety, dizziness, rhinitis, insomnia, diarrhea, etc.
Speaking about serious side effects, cases of toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, and Stevens-Johnson syndrome have been registered in postmarketing surveillance.
These rashes that are dangerous for life connected with the Modafinil drug appear extremely rare.
However, accurate rates of incidence are not established.
The majority of the registered cases have occurred within six weeks of medication use initiation.
That’s why if you start to experience a rash during this time frame, it is recommended to contact your healthcare provider as fast as possible.
Abuse Potential
Certain clinical trials show that the use of the Modafinil drug produces euphoric and psychoactive effects, changing mood, perception, thinking, and feelings like other central nervous system stimulants.
That’s why patients with a history of drug abuse should evaluate the risk of potential abuse and take the Modafinil medication carefully.
Contraindications
There are several absolute contraindications to the use of the Modafinil drug. Nevertheless, it is necessary to be aware of the relative contraindications, cautions, and special considerations.
For instance, if a serious rash develops, you should stop taking the Modafinil medication at the first sign of a rash.
Also, if you suspect angioedema and anaphylaxis reactions, stop taking Modafinil as well. Likewise, if multiorgan hypersensitivity reactions are suspected, discontinue Modafinil use.
Speaking about other contraindications, it isn’t advisable to take Modafinil by patients with documented left-ventricular hypertrophy or a history of previous cardiotoxicity connected with psychostimulant use.
Modafinil should be likewise employed carefully by individuals with recent myocardial infarction, uncontrolled hypertension, and unstable angina. Moreover, the Modafinil medication should be taken with caution by individuals with a history of psychosis and/or mania.
Summary
To conclude we can say that Modafinil is a stimulant medication that is relatively well-tolerated and secure for patients. Modafinil has a low potential for abuse and dependence.
This drug is employed for the treatment of excessive daytime sleepiness connected with narcolepsy, shift work sleep disorder, and obstructive sleep apnea.
Modafinil is likewise usually taken in combination with other medical and lifestyle treatments for these conditions.
The majority of individuals may take the Modafinil medication securely.
Nevertheless, it should be employed with caution by patients with a history of psychosis/mania, structural cardiac disease, recent myocardial infarction, etc. Contact your healthcare provider to determine whether Modafinil is safe to use by you.
Moreover, your healthcare provider will monitor the treatment with Modafinil to be passed effectively and manage side effects if appeared.
Frequently Asked Questions
Can I get Modafinil without prescription?
Modafinil is a prescription-only drug. Selling or giving away the Modafinil medication is against the law.
What should I do if I forget to take a dose of Modafinil?
It is recommended to skip the missed dose. The best idea is to wait until the next time you should take the Modafinil drug, and after that take your normal dose.
Are there any side effects from Modafinil?
As a rule, Modafinil may create certain side effects such as headache, diarrhea, dizziness, loss of appetite, etc. If you experience these or other side effects from taking Modafinil, you should hasten to contact your healthcare provider as quickly as possible.
Is Modafinil secure?
Modafinil is a safe-to-use medication. The main rule is to take Modafinil as prescribed by your healthcare provider.